Clinicaltrials
warningsgateway.pipeworx.io
ClinicalTrials MCP — wraps ClinicalTrials.gov API v2 (free, no auth)
https://gateway.pipeworx.io/clinicaltrials/mcpWebsiteOAuthMCP 2025-03-26v0.1.0last checked 3 Sep 2026spoke MCP on 3 of 3 checks (30 days)initialize in 110 msWill my client connect?
Decided from what the probe found at the endpoint, and from what each client's own documentation says it can complete. Every row carries the day that documentation was read.
✓Claude CodeConnects
The authorization server advertises RFC 7591 registration, so Claude Code can register itself and sign you in through the browser.
claude mcp add --transport http clinicaltrials https://gateway.pipeworx.io/clinicaltrials/mcpClaude Code docs · read on 2026-08-30
✓Claude (claude.ai & Desktop)Connects
The authorization server advertises RFC 7591 registration, so Claude (claude.ai & Desktop) can register itself and sign you in through the browser.
Settings → Connectors → Add custom connector, then paste https://gateway.pipeworx.io/clinicaltrials/mcp.
Claude (claude.ai & Desktop) docs · read on 2026-08-30
✓ChatGPTConnects
The authorization server advertises RFC 7591 registration, so ChatGPT can register itself and sign you in through the browser.
Settings → Apps → Advanced settings → Developer mode, then create a connector pointing at https://gateway.pipeworx.io/clinicaltrials/mcp.
ChatGPT docs · read on 2026-08-30
✓CursorConnects
The authorization server advertises RFC 7591 registration, so Cursor can register itself and sign you in through the browser.
{
"mcpServers": {
"clinicaltrials": {
"url": "https://gateway.pipeworx.io/clinicaltrials/mcp"
}
}
}Cursor docs · read on 2026-08-30
✓VS Code (Copilot)Connects
The authorization server advertises RFC 7591 registration, so VS Code (Copilot) can register itself and sign you in through the browser.
{
"servers": {
"clinicaltrials": {
"type": "http",
"url": "https://gateway.pipeworx.io/clinicaltrials/mcp"
}
}
}VS Code (Copilot) docs · read on 2026-08-30
How to authenticate
Checked against the endpoint by our probe on 3 Sep 2026. These are the capabilities the server advertises, not a prediction about any particular client.
| Scheme | OAuth |
|---|---|
| Issuer | https://gateway.pipeworx.io |
| Dynamic client registration | ✓Advertised (RFC 7591) |
| Client ID Metadata Document | ✓Supported A client identifies itself by a URL to its own metadata, so no registration step is required. |
| PKCE | ✓S256 |
| Grant types | authorization_code, refresh_token |
| Scopes | pipeworx:read |
| Protected-resource metadata | ✓Published (RFC 9728) |
| Anonymous access | Handshake succeeds; 44 tools listable |
| Credentials demanded in prose | ✕deep_research, subscribe These tools are listed anonymously and their own descriptions ask for an account or key, but no challenge is issued — so a client has nothing to act on and the refusal arrives as a tool error. |
| Documentation | https://pipeworx.io/install |
What the probe found
2 of the 44 tools listed anonymously say in their own descriptions that they need an account or a key (deep_research, subscribe), but the endpoint issued no WWW-Authenticate challenge. The requirement is stated only in prose, so a call reaches the tool and comes back as a tool error instead of an authorization step.
The server exposes a public surface before authorization: ask_pipeworx, ask_pipeworx_beta, ask_pipeworx_grounded, search_within, deep_research, discover_tools, resolve_entity, compare_entities, subscribe, unsubscribe, list_subscriptions, recent_alerts, entity_profile, recent_changes, validate_claim, scan_dependency, bet_research, polymarket_arbitrage, polymarket_edges, polymarket_kalshi_spread, polymarket_fill_risk, polymarket_edge_tracker, pipeworx_trending, suggest_questions, generate_llms_txt, ai_visibility_check, scan_competitor_ai_presence, pipeworx_feedback, remember, recall, forget, ct_search, ct_get_study, ct_count_by_condition, ct_sponsor_trials, ct_compare_sponsors, ct_recent_updates, ct_trials_by_location, ct_catalyst_calendar, ct_sponsor_pipeline, ct_competitive_landscape, ct_enrollment_watch, ct_results_summary, ct_sponsor_activity.
Tools
Contract history
Instructions rewritten: ask_pipeworx, ask_pipeworx_beta, ask_pipeworx_grounded, deep_research, polymarket_kalshi_spread. The description an agent follows changed; the callable contract may not have.
Instructions rewritten: ask_pipeworx, ask_pipeworx_beta, ask_pipeworx_grounded, deep_research. The description an agent follows changed; the callable contract may not have.
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Status badge
Status for a README, from the last probe — cached an hour, so up to seven hours behind the endpoint. Links back to this page.
[](https://mcpi.app/servers/clinicaltrials)